SCHEMBL78005

SCHEMBL78005

CCCC(Nc1nc(NCCO)nc(NC(CCC)C2CC(C)(C)N(OC3CCCCC3)C(C)(C)C2)n1)C1CC(C)(C)N(OC2CCCCC2)C(C)(C)C1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HRH4 Q9H3N8 1/20 0.32
CCNB2 O95067 1/20 0.32
CCNB1 P14635 1/20 0.32
CCNA2 P20248 1/20 0.32
CDK2 P24941 1/20 0.32
CCNA1 P78396 1/20 0.32
CCNB3 Q8WWL7 1/20 0.32
GBA1 P04062 8/20 0.32
SLC29A1 Q99808 3/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9428557 0.96 KMT2A (0.37) CDK1ALDH1A1HRH4CCNB2CCNB1
SCHEMBL9428450 0.93 KMT2A (0.37) GBA1SLC29A1KMT2A
SCHEMBL9207772 0.91 ADAMTS5 (0.33) HRH4
SCHEMBL1231052 0.91 IDH1 (0.31)
SCHEMBL9429157 0.89 KDM4E (0.34) KMT2A
SCHEMBL9428172 0.89 CDK1 (0.31) CDK1
SCHEMBL6300707 0.88 HRH4 (0.33) HRH4GBA1
SCHEMBL9429076 0.87 IDH2 (0.35) GBA1
SCHEMBL9428468 0.87 HTR7 (0.33)
SCHEMBL9429082 0.87 KMT2A (0.37) ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 748 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240084104-A1 ADDITIVE MIXTURES BASF SE (DE) 2024-03-14 US claimed
US-20240052141-A1 AN ORGANIC MATERIAL BASED SHAPED ARTICLE BASF SE (DE) 2024-02-15 US claimed
US-11623979-B2 Stabilized polyolefin compositions comprising benzofuranones and hindered amine light stabilizers BASF SE (DE) 2023-04-11 US claimed
US-20220282064-A1 STABILIZER COMPOSITION BASF SE (DE) 2022-09-08 US claimed
EP-3841166-B1 STABILIZED ROTOMOLDED POLYOLEFIN BASF SE (DE) 2022-07-20 EP claimed
US-20210301102-A1 STABILIZED ROTOMOLDED POLYOLEFIN BASF SE (DE) 2021-09-30 US claimed
EP-3841166-A1 STABILIZED ROTOMOLDED POLYOLEFIN BASF SE (DE) 2021-06-30 EP claimed
US-10941286-B2 Stabilized polyolefin compositions comprising benzofuranones and hindered amine light stabilizers BASF SE (DE) 2021-03-09 US claimed
US-20200216638-A1 Stabilized Polyolefin Compositions Comprising Benzofuranones and Hindered Amine Light Stabilizers BASF SCHWEIZ AG (CH) 2020-07-09 US claimed
EP-3649137-A1 STABILIZED POLYOLEFIN COMPOSITIONS COMPRISING BENZOFURANONES AND HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2020-05-13 EP claimed
EP-1664128-B1 WATER BASED CONCENTRATED PRODUCT FORMS OF LIGHT STABILIZERS MADE BY A HETEROPHASE POLYMERIZATION TECHNIQUE CIBA HOLDING INC (CH) 2009-01-21 EP claimed
EP-1676887-B1 Composition and process for improving heat and weathering stability of segmented polyurethane polymers CIBA SC HOLDING AG (CH) 2007-05-23 EP claimed
US-20060287416-A1 Water based concetrated product forms of light stabilizers made by a heterophase polymerization technique CIBA SPECIALTY CHEMICALS CORP. 2006-12-21 US claimed
EP-1646681-B1 FLAME RETARDANT POLYLACTIC ACID CIBA SC HOLDING AG (CH) 2006-11-29 EP claimed
EP-1676887-A1 Composition and process for improving heat and weathering stability of segmented polyurethane polymers Ciba Specialty Chemicals Holding Inc. (CH) 2006-07-05 EP claimed
US-20060142441-A1 Composition and process for improving heat and weathering stability of segmented polyurethane polymers CIBA SPECIALTY CHEMICALS CORP. 2006-06-29 US claimed
EP-1664128-A1 WATER BASED CONCENTRATED PRODUCT FORMS OF LIGHT STABILIZERS MADE BY A HETEROPHASE POLYMERIZATION TECHNIQUE Ciba SC Holding AG (CH) 2006-06-07 EP claimed
WO-2005023878-A1 WATER BASED CONCENTRATED PRODUCT FORMS OF LIGHT STABILIZERS MADE BY A HETEROPHASE POLYMERIZATION TECHNIQUE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-03-17 WO claimed
US-6740132-B2 Stabilized against color fade or color change by a combination of a UV absorber and a metal compound, particularly a tin compound; may also contain hindered amine or antioxidant CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-25 US claimed
US-6562085-B1 Against discoloration and fading; antioxidant; benzotriazole-metal complex or benzotriazole-metal salt compounds CIBA SPECIALTY CHEMICALS CORPORATION 2003-05-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10941286-B2 Stabilized polyolefin compositions comprising benzofuranones and hindered amine light stabilizers PUF60, PARG, PARN CDK1 712/4885ALDH1A1 1248/4885HRH4 3364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.