SCHEMBL9428294

CCCC(Nc1nc(NCCCCCCNc2nc(NC3CC(C)(C)N(OC4CCCCC4)C(C)(C)C3)nc(NC(CCC)C3CC(C)(C)N(OC4CCCCC4)C(C)(C)C3)n2)nc(NC2CC(C)(C)N(OC3CCCCC3)C(C)(C)C2)n1)C1CC(C)(C)N(OC2CCCCC2)C(C)(C)C1

nearest known ligand 0.34

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	FLT3	P36888	2/20	0.32

▸	TYRO3	Q06418	2/20	0.32

▸	MERTK	Q12866	2/20	0.32

▸	GAS6	Q14393	2/20	0.32

▸	EHMT2	Q96KQ7	3/20	0.31

▸	EHMT1	Q9H9B1	3/20	0.31

▸	CTSS	P25774	1/20	0.31

▸	CTSK	P43235	1/20	0.31

▸	ALDH1A1	P00352	1/20	0.30

▸	CDK1	P06493	1/20	0.30

▸	CDK2	P24941	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9207772	0.91	ADAMTS5 (0.33)	FLT3TYRO3MERTKGAS6EHMT2
SCHEMBL9429082	0.90	KMT2A (0.37)	ALDH1A1
SCHEMBL9428557	0.90	KMT2A (0.37)	ALDH1A1CDK1CDK2
SCHEMBL9428468	0.90	HTR7 (0.33)	—
SCHEMBL9427998	0.87	FFAR4 (0.32)	FLT3TYRO3MERTKGAS6
SCHEMBL1231052	0.87	IDH1 (0.31)	—
SCHEMBL78005	0.86	CDK1 (0.33)	ALDH1A1CDK1CDK2
SCHEMBL9428559	0.85	—	—
SCHEMBL9428436	0.85	—	—
SCHEMBL9428567	0.84	EHMT2 (0.34)	FLT3TYRO3MERTKGAS6EHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5300544-A	Non-migrating 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperdine 1,3,5-triazine derivatives as polymer stabilizers	CIBA-GEIGY CORPORATION (US)	1994-04-05	—	—	US	disclosed