SCHEMBL920781

SCHEMBL920781

COc1ccccc1Oc1cc[c]c(F)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.53
L3MBTL1 Q9Y468 3/20 0.53
ALDH1A1 P00352 2/20 0.53
MAPK1 P28482 1/20 0.53
AR P10275 2/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
TDP1 Q9NUW8 1/20 0.37
TTR P02766 3/20 0.36
RAB9A P51151 1/20 0.36
MAPT P10636 1/20 0.36
TSHR P16473 1/20 0.35
BCHE P06276 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920832 0.83 AR (0.43) ALDH1A1ARKMT2AMEN1RAB9A
SCHEMBL919322 0.83 PARP10 (0.42) ALDH1A1KMT2AMEN1
SCHEMBL20240552 0.81 HTT (0.55) HTTL3MBTL1ALDH1A1MAPK1AR
SCHEMBL919701 0.80 AR (0.43) HTTALDH1A1ARKMT2A
SCHEMBL919676 0.78 SMN1; SMN2 (0.50) L3MBTL1ALDH1A1CA1CA2CA7
SCHEMBL4242 0.78
SCHEMBL921863 0.77 LTA4H (0.45) HTTL3MBTL1ALDH1A1MAPK1CA12
SCHEMBL921217 0.77 PARP10 (0.53) ALDH1A1MAPK1KMT2AMEN1MAPT
SCHEMBL920762 0.77 LTA4H (0.48) HTTALDH1A1MAPK1CA1CA2
SCHEMBL8132583 0.77 EGLN1 (0.38) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HTT 2561/4885L3MBTL1 1292/4885ALDH1A1 2743/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 HTT 450/4885L3MBTL1 779/4885ALDH1A1 4326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.