Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205660 | 0.87 | GRM5 (0.42) | CYP2D6KDM4EEEDITGB3ITGA2B | |
| SCHEMBL9213734 | 0.84 | GRM5 (0.41) | CYP2D6KDM4EEEDITGB3ITGA2B | |
| SCHEMBL9207673 | 0.82 | MEN1 (0.47) | ITGB3ITGA2B | |
| SCHEMBL9214577 | 0.81 | KDM4E (0.42) | CYP2D6KDM4EITGB3ITGA2B | |
| SCHEMBL9740567 | 0.79 | DRD2 (0.41) | NAAACYP2D6KDM4EACP1EED | |
| SCHEMBL9207567 | 0.76 | DRD2 (0.39) | NAAACYP2D6KDM4EACP1EED | |
| SCHEMBL9211986 | 0.76 | KDM4E (0.42) | CYP2D6KDM4EDRD1DRD5HRH3 | |
| SCHEMBL9667738 | 0.75 | CYP2D6 (0.46) | CYP2D6KDM4EDRD1DRD5HRH3 | |
| SCHEMBL9204844 | 0.75 | MEN1 (0.49) | — | |
| Hydrochloric Acid SCHEMBL9667493 | 0.74 | CYP2D6 (0.45) | CYP2D6KDM4EDRD1DRD5HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| EP-0292840-A2 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |