Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924069 | 0.93 | LMNA (0.43) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7502083 | 0.90 | ALDH1A1 (0.36) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7498541 | 0.89 | ALDH1A1 (0.36) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9211202 | 0.89 | KDM4E (0.43) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7494670 | 0.87 | KDM4E (0.35) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7494808 | 0.87 | ALDH1A1 (0.36) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7498548 | 0.87 | ALDH1A1 (0.35) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9215646 | 0.85 | KMT2A (0.38) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7847782 | 0.83 | ALDH1A1 (0.41) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7843329 | 0.81 | ALDH1A1 (0.41) | LMNAKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589318-B1 | Antibacterial 7-(aminomethyl-oxa-7-azabicyclo(3.3.0)oct-7-yl)quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1995-11-15 | — | — | EP | disclosed |
| EP-0589318-A2 | Antibacterial 7-(aminomethyl-oxa-7-azabicyclo(3.3.0)oct-7-yl)quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1994-03-30 | — | — | EP | disclosed |