Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | MITF | O75030 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | TOP2A | P11388 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198215 | 0.90 | SOD1 (0.53) | LMNAKMT2ASMARCA2MEN1MITF | |
| SCHEMBL9210266 | 0.86 | ACHE (0.57) | KMT2ASMARCA2MEN1POLBACHE | |
| SCHEMBL9206825 | 0.84 | KAT2B (0.55) | LMNAKMT2ASMARCA2MEN1MITF | |
| SCHEMBL9206353 | 0.82 | LMNA (0.46) | LMNAKMT2ASMARCA2MEN1MITF | |
| SCHEMBL28961846 | 0.81 | TOP2A (0.56) | LMNAKMT2AMEN1POLBHPGD | |
| SCHEMBL29291218 | 0.77 | CYP1A2 (0.59) | LMNAKMT2ASMARCA2MEN1MITF | |
| SCHEMBL1752978 | 0.76 | LMNA (0.80) | LMNACYP3A4ACHECYP1A2CYP2D6 | |
| SCHEMBL9203425 | 0.76 | MALT1 (0.63) | LMNAKMT2AMEN1POLBCYP3A4 | |
| SCHEMBL9870727 | 0.75 | LMNA (0.53) | LMNAKMT2ASMARCA2CYP3A4ACHE | |
| SCHEMBL1752928 | 0.75 | ACHE (0.63) | LMNACYP3A4ACHECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497809-B1 | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES | BOEHRINGER MANNHEIM ITALIA (IT) | 1995-06-28 | — | — | EP | disclosed |
| US-5162320-A | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1992-11-10 | — | — | US | disclosed |
| EP-0497809-A1 | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES. | BOEHRINGER MANNHEIM ITALIA (IT) | 1992-08-12 | — | — | EP | disclosed |
| WO-1991006540-A1 | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1991-05-16 | — | — | WO | disclosed |