SCHEMBL920848

SCHEMBL920848

Nc1ncccc1C(=O)NCc1cccc(Oc2cccnc2)c1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.53
KMT2A Q03164 2/20 0.53
MAPK8 P45983 1/20 0.51
USP2 O75604 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HCRTR1 O43613 1/20 0.48
HCRTR2 O43614 1/20 0.48
TSHR P16473 1/20 0.47
RECQL P46063 1/20 0.47
MMP13 P45452 1/20 0.46
NPC1 O15118 1/20 0.46
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1680406 0.90 MAPK8 (0.63) HPGDKMT2AMAPK8USP2KDM4E
SCHEMBL920569 0.89 MAPK8 (0.56) HPGDMAPK8USP2ALDH1A1TSHR
SCHEMBL920646 0.88 HPGD (0.59) HPGDKMT2AMAPK8USP2KDM4E
SCHEMBL921259 0.87 KMT2A (0.53) HPGDKMT2AMAPK8USP2KDM4E
SCHEMBL921817 0.87 HPGD (0.53) HPGDKMT2AMAPK8USP2KDM4E
SCHEMBL920078 0.87 HPGD (0.56) HPGDKMT2AMAPK8USP2KDM4E
SCHEMBL923218 0.87 HPGD (0.53) HPGDKMT2AMAPK8USP2KDM4E
SCHEMBL920826 0.87 HPGD (0.53) HPGDKMT2AMAPK8USP2KDM4E
SCHEMBL920983 0.87 HPGD (0.67) HPGDKMT2AUSP2KDM4EALDH1A1
SCHEMBL13070670 0.87 HPGD (0.53) HPGDKMT2AMAPK8USP2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885KMT2A 2469/4885MAPK8 2313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.