SCHEMBL920569

SCHEMBL920569

Nc1ncccc1C(=O)NCc1ccc(Oc2cccnc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 1/20 0.56
MMP13 P45452 2/20 0.50
HPGD P15428 3/20 0.49
LMNA P02545 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
HTT P42858 2/20 0.49
CYP3A4 P08684 1/20 0.49
MAPK14 Q16539 1/20 0.49
FAAH O00519 1/20 0.48
ALDH1A1 P00352 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
NPC1 O15118 1/20 0.47
GAA P10253 1/20 0.47
RAB9A P51151 1/20 0.47
NAMPT P43490 1/20 0.47
USP2 O75604 1/20 0.47
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920461 0.91 MAPK8 (0.67) MAPK8MMP13HPGDLMNASMN1; SMN2
SCHEMBL920848 0.89 HPGD (0.53) MAPK8MMP13HPGDHTTALDH1A1
SCHEMBL922025 0.86 ALDH1A1 (0.58) MAPK8HPGDLMNASMN1; SMN2HTT
SCHEMBL922484 0.86 HPGD (0.62) MAPK8MMP13HPGDLMNASMN1; SMN2
SCHEMBL920221 0.86 MAPK8 (0.55) MAPK8MMP13HPGDLMNASMN1; SMN2
SCHEMBL921037 0.86 HPGD (0.66) MAPK8HPGDLMNASMN1; SMN2ALDH1A1
SCHEMBL920343 0.86 KMT2A (0.61) MAPK8HPGDLMNASMN1; SMN2CYP3A4
SCHEMBL920265 0.86 MAPK8 (0.55) MAPK8MMP13HPGDLMNASMN1; SMN2
SCHEMBL920473 0.86 HPGD (0.57) MAPK8HPGDLMNASMN1; SMN2ALDH1A1
SCHEMBL920793 0.85 LMNA (0.61) MAPK8HPGDLMNASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAPK8 2313/4885MMP13 4062/4885HPGD 1273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.