Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | EPHB3 | P54753 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215003 | 0.89 | MAPT (0.50) | KDM4ELMNAMAPTPDE4DNPC1 | |
| SCHEMBL9588701 | 0.80 | MAPT (0.51) | KDM4ELMNAMAPTPDE4DNPC1 | |
| SCHEMBL9214998 | 0.77 | KDM4E (0.53) | KDM4ELMNAMAPTNPC1POLB | |
| SCHEMBL5201549 | 0.74 | GRM5 (0.62) | KDM4ELMNAMAPTNPC1KMT2A | |
| SCHEMBL4699328 | 0.73 | PDE4D (0.69) | MAPTPDE4DNPC1POLBCASP3 | |
| SCHEMBL982701 | 0.69 | HPGD (0.59) | KDM4EMAPTPOLBATMKMT2A | |
| SCHEMBL1077553 | 0.69 | NPC1 (0.53) | KDM4ELMNAMAPTNPC1POLB | |
| SCHEMBL9678143 | 0.68 | KDM4E (0.42) | KDM4ELMNAMAPTPDE4DATM | |
| SCHEMBL27348211 | 0.68 | KDM4E (0.56) | KDM4ELMNAMAPTNPC1POLB | |
| SCHEMBL10689341 | 0.66 | NPC1 (0.58) | KDM4ELMNAMAPTNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422456-B1 | Pyridine derivatives and their use in combating unwanted plant growth | BASF AG (DE) | 1995-05-03 | — | — | EP | disclosed |
| EP-0422456-A2 | Pyridine derivatives and their use in combating unwanted plant growth | BASF Aktiengesellschaft (DE) | 1991-04-17 | — | — | EP | disclosed |