Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.42 |
| ▸ | FYN | P06241 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570505 | 0.83 | — | — | |
| SCHEMBL9177576 | 0.76 | AGTR1 (0.40) | — | |
| SCHEMBL9660639 | 0.75 | AGTR1 (0.38) | — | |
| SCHEMBL9175146 | 0.75 | PDK2 (0.36) | PDK2 | |
| SCHEMBL9489948 | 0.75 | ATM (0.44) | — | |
| SCHEMBL9171970 | 0.75 | ITGB1 (0.33) | — | |
| SCHEMBL9177502 | 0.74 | AGTR1 (0.37) | — | |
| SCHEMBL9464089 | 0.73 | TRPA1 (0.31) | TSHR | |
| SCHEMBL1034309 | 0.69 | ENPP2 (0.31) | — | |
| SCHEMBL9205048 | 0.68 | KCNN4 (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685467-A1 | NOVEL PYRIMIDINE DERIVATIVE AND MEDICINAL COMPOSITION | NKK CORPORATION (JP) | 1995-12-06 | — | — | EP | disclosed |
| EP-0654030-A1 | IMIDAZOLE DERIVATIVES HAVING A II ANTAGONIST ACTIVITY. | LUSO FARMACO INST (IT) | 1995-05-24 | — | — | EP | disclosed |