Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 3/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203141 | 0.89 | NPC1 (0.64) | CCKBR | |
| SCHEMBL9203429 | 0.85 | CCKBR (0.80) | CCKBR | |
| SCHEMBL21323255 | 0.79 | NPC1 (0.76) | — | |
| SCHEMBL12566777 | 0.77 | LMNA (0.56) | CCKBR | |
| SCHEMBL29934873 | 0.77 | CCKBR (1.00) | CCKBR | |
| SCHEMBL9002941 | 0.77 | CCKBR (1.00) | CCKBR | |
| SCHEMBL16346179 | 0.76 | NPC1 (0.67) | — | |
| SCHEMBL28451012 | 0.76 | MEN1 (0.78) | — | |
| SCHEMBL16346218 | 0.74 | MAPK1 (0.64) | — | |
| SCHEMBL734714 | 0.73 | NPC1 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475755-B1 | 3-Aryl-4(3H)quinazolinone CCK antagonists and pharmaceutical formulations thereof | LILLY CO ELI (US) | 1995-09-27 | — | — | EP | disclosed |
| US-5196427-A | Gastrointestinal and central nervous system disorders; hormone inhibitors | ELI LILLY AND COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0475755-A1 | 3-Aryl-4(3H)quinazolinone CCK antagonists and pharmaceutical formulations thereof | ELI LILLY AND COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| US-5075313-A | For bindign to cholecystokinin receptors | ELI LILLY AND COMPANY (US) | 1991-12-24 | — | — | US | disclosed |