SCHEMBL920950

SCHEMBL920950

Nc1ncccc1C(=O)NCc1cccc(-c2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 3/20 0.56
AOC3 Q16853 2/20 0.54
PRKCI P41743 1/20 0.52
LIPG Q9Y5X9 1/20 0.52
MAPK8 P45983 1/20 0.51
ATM Q13315 1/20 0.51
HTT P42858 1/20 0.51
KMT2A Q03164 1/20 0.51
GALR3 O60755 1/20 0.51
NR2F2 P24468 1/20 0.51
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MAPK1 P28482 1/20 0.50
CHRNB2 P17787 1/20 0.50
CHRNB4 P30926 1/20 0.50
CHRNA3 P32297 1/20 0.50
CHRNA4 P43681 1/20 0.50
CFD P00746 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922251 0.88 GALR3 (0.60) NSD2PRKCIMAPK8ATMHTT
SCHEMBL922492 0.88 NSD2 (0.66) NSD2PRKCIMAPK8ATMKMT2A
SCHEMBL922032 0.88 NSD2 (0.56) NSD2PRKCIMAPK8ATMKMT2A
SCHEMBL923436 0.88 NSD2 (0.56) NSD2PRKCIMAPK8ATMKMT2A
SCHEMBL27803858 0.85 NSD2 (0.52) NSD2PRKCIMAPK8ATMKMT2A
SCHEMBL921415 0.85 ROCK2 (0.53) NSD2PRKCIMAPK8ATMKMT2A
SCHEMBL1680406 0.84 MAPK8 (0.63) NSD2MAPK8KMT2AKDM4EALDH1A1
SCHEMBL922705 0.84 ATM (0.63) NSD2PRKCIMAPK8ATMKMT2A
SCHEMBL922542 0.84 ROCK1 (0.57) NSD2KMT2AKDM4EALDH1A1HPGD
SCHEMBL920245 0.84 HPGD (0.54) NSD2PRKCIMAPK8ATMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 NSD2 1533/4885AOC3 1489/4885PRKCI 3037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.