Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439285 | 0.78 | ALOX5 (0.60) | ALOX5LMNATMEM97 | |
| SCHEMBL9209888 | 0.76 | PDK1 (0.55) | ALOX5MAPT | |
| SCHEMBL9743956 | 0.75 | ALOX5 (0.48) | ALOX5MAPTLMNATP53THRB | |
| SCHEMBL9439503 | 0.71 | ALOX5 (0.58) | ALOX5LMNATMEM97 | |
| SCHEMBL9216935 | 0.71 | TMEM97 (0.44) | MAPTTMEM97 | |
| SCHEMBL9744858 | 0.70 | ALOX5 (0.55) | ALOX5MAPTLMNATP53 | |
| SCHEMBL9206730 | 0.69 | — | — | |
| SCHEMBL9439898 | 0.69 | MAPT (0.63) | ALOX5MAPTLMNATP53 | |
| SCHEMBL9217493 | 0.68 | CYP1A2 (0.44) | ALOX5MAPTTHRB | |
| SCHEMBL30881402 | 0.68 | MAPT (0.41) | MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405976-B1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA CO (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5200407-A | Antisecretory agents | MEIJI SEIKA KABURHIKI KAISHA (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5141946-A | Antisecretory agents; acid resistance | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5079255-A | Nontoxic, acid stability | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0405976-A1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-01-02 | — | — | EP | disclosed |