SCHEMBL920994

SCHEMBL920994

Cc1ccc(C(C)c2ccc(C)c(O)c2C)c(C)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
TRPA1 O75762 4/20 0.37
LMNA P02545 2/20 0.37
PTGS1 P23219 2/20 0.37
SLC6A2 P23975 2/20 0.37
HTR2B P41595 2/20 0.37
CYP1A2 P05177 2/20 0.37
GABRA1 P14867 2/20 0.37
GABRB2 P47870 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
HPGD P15428 2/20 0.37
FAAH O00519 1/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
GABRB1 P18505 1/20 0.37
GABRG2 P18507 1/20 0.37
HTR2C P28335 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRA5 P31644 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29477364 0.88 GABRA1 (0.46) ALDH1A1TRPA1LMNAPTGS1SLC6A2
SCHEMBL3927190 0.88 GABRA1 (0.46) ALDH1A1TRPA1LMNAPTGS1SLC6A2
SCHEMBL14600343 0.86 ALDH1A1 (0.39) ALDH1A1TRPA1LMNAPTGS1SLC6A2
SCHEMBL10585574 0.85 ALDH1A1 (0.42) ALDH1A1TRPA1LMNAPTGS1SLC6A2
SCHEMBL922064 0.83 PTGS1 (0.40) ALDH1A1TRPA1LMNAPTGS1SLC6A2
SCHEMBL4385373 0.78 GRM1 (0.36) ALDH1A1TRPA1LMNAPTGS1SLC6A2
SCHEMBL44351 0.78 ALDH1A1 (0.62) ALDH1A1TRPA1LMNAPTGS1SLC6A2
SCHEMBL1494556 0.77 GABRA1 (0.56) ALDH1A1TRPA1LMNAPTGS1SLC6A2
SCHEMBL4096080 0.76 GABRA1 (0.39) ALDH1A1TRPA1LMNAPTGS1SLC6A2
SCHEMBL30940221 0.76 ALDH1A1 (0.34) ALDH1A1TRPA1CYP1A2GRM1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481238-B2 Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2013-07-09 US disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-7985522-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-26 US disclosed
EP-1770447-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY MITSUBISHI CHEM CORP (JP) 2011-03-16 EP disclosed
US-20110013934-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2011-01-20 US disclosed
US-20100183332-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTORS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-07-22 US disclosed
EP-2154575-A2 Electrophotographic photoreceptor Mitsubishi Chemical Corporation (JP) 2010-02-17 EP disclosed
US-7604913-B2 Electrophotographic photosensitive body MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-20 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090047589-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-19 US disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 US disclosed
EP-1770447-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Mitsubishi Chemical Corporation (JP) 2007-04-04 EP disclosed