SCHEMBL4385373

SCHEMBL4385373

CCC(c1ccc(C)c(O)c1C)c1ccc(C)c(O)c1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM1 Q13255 1/20 0.36
ALDH1A1 P00352 2/20 0.36
TSHR P16473 3/20 0.34
HPGD P15428 2/20 0.34
GAA P10253 2/20 0.34
CYP1A2 P05177 4/20 0.33
CYP3A4 P08684 3/20 0.33
CYP2C9 P11712 3/20 0.33
CYP2C19 P33261 3/20 0.33
BCHE P06276 2/20 0.33
TYR P14679 2/20 0.33
ACHE P22303 2/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TRPA1 O75762 1/20 0.32
ELANE P08246 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
HKDC1 Q2TB90 1/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23202772 0.85 TSHR (0.44) GRM1ALDH1A1TSHRHPGDGAA
SCHEMBL9770066 0.80 GPR84 (0.34) TSHRHPGDGAASMN1; SMN2GPR84
SCHEMBL920994 0.78 ALDH1A1 (0.42) GRM1ALDH1A1TSHRHPGDCYP1A2
SCHEMBL10585574 0.78 ALDH1A1 (0.42) GRM1ALDH1A1TSHRHPGDGAA
SCHEMBL11686897 0.77 TYR (0.39) ALDH1A1TSHRHPGDGAACYP1A2
SCHEMBL9482716 0.77 ALDH1A1 (0.54) ALDH1A1TSHRHPGDGAACYP1A2
SCHEMBL9500586 0.76 HTR1D (0.38) GRM1ALDH1A1TSHRHPGDGAA
SCHEMBL29477364 0.76 GABRA1 (0.46) GRM1ALDH1A1TSHRHPGDCYP1A2
SCHEMBL3927190 0.76 GABRA1 (0.46) GRM1ALDH1A1TSHRHPGDCYP1A2
SCHEMBL9722058 0.75 ESR1 (0.38) ALDH1A1TSHRGAACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed