Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220492 | 0.92 | MCL1 (0.65) | MCL1MAPTCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL9212323 | 0.91 | L3MBTL1 (0.51) | MCL1MAPTCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL9220313 | 0.89 | MCL1 (0.57) | MCL1MAPTCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL9217469 | 0.89 | KDM4E (0.54) | MCL1MAPTCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL9431056 | 0.89 | MAPT (0.53) | MCL1MAPTCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL9219841 | 0.88 | MCL1 (0.63) | MCL1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL8201626 | 0.87 | L3MBTL1 (0.60) | MCL1MAPTTP53KDM4EMEN1 | |
| SCHEMBL9221054 | 0.86 | MAPT (0.54) | MCL1MAPTCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL9209323 | 0.86 | L3MBTL1 (0.47) | MCL1MAPTCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL9430174 | 0.85 | KDM4E (0.59) | MCL1MAPTCSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| WO-1994026738-A1 | N'-HETEROCYCLYL-N-BENZOFURANYL UREA DERIVATIVES AND THEIR ANALOGS AS ACAT INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |