Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210201 | 0.89 | MCL1 (0.57) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL9431056 | 0.89 | MAPT (0.53) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL9430174 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL9212898 | 0.81 | MAPT (0.48) | KDM4EALDH1A1HPGDMAPTTP53 | |
| SCHEMBL9220492 | 0.81 | MCL1 (0.65) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL9209992 | 0.80 | TP53 (0.53) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL9218384 | 0.80 | TP53 (0.54) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL9216793 | 0.80 | POLB (0.58) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL9215004 | 0.80 | NPC1 (0.47) | MAPTTP53CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL9430247 | 0.80 | MAPT (0.58) | KDM4EALDH1A1HPGDMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |