Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201626 | 0.92 | L3MBTL1 (0.60) | L3MBTL1MAPTATMKDM4ENPC1 | |
| SCHEMBL9221054 | 0.91 | MAPT (0.54) | L3MBTL1MAPTATMKDM4ENPC1 | |
| SCHEMBL9209323 | 0.91 | L3MBTL1 (0.47) | L3MBTL1MAPTATMKDM4ENPC1 | |
| SCHEMBL9210201 | 0.91 | MCL1 (0.57) | L3MBTL1MAPTATMKDM4ENPC1 | |
| SCHEMBL9220492 | 0.88 | MCL1 (0.65) | MAPTKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL9213858 | 0.87 | L3MBTL1 (0.49) | L3MBTL1MAPTATMKDM4ENPC1 | |
| SCHEMBL9212898 | 0.86 | MAPT (0.48) | L3MBTL1MAPTATMKDM4ENPC1 | |
| SCHEMBL9219744 | 0.84 | PTPN1 (0.56) | L3MBTL1MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL9430877 | 0.81 | TP53 (0.54) | L3MBTL1MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL1065472 | 0.80 | MCL1 (0.71) | L3MBTL1MAPTKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |