Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209250 | 1.00 | EPHX2 (0.40) | EPHX2ALOX5ALDH1A1ALOX15TDP1 | |
| SCHEMBL9205591 | 0.94 | EPHX2 (0.36) | EPHX2ALOX5ALDH1A1ALOX15TDP1 | |
| SCHEMBL9206833 | 0.87 | GAA (0.37) | EPHX2ALDH1A1ALOX15GAA | |
| SCHEMBL8430751 | 0.87 | KDM5A (0.38) | EPHX2 | |
| SCHEMBL536568 | 0.84 | KDM5A (0.35) | EPHX2ALDH1A1ALOX15GAA | |
| SCHEMBL11059443 | 0.82 | EPHX2 (0.37) | EPHX2ALDH1A1ALOX15TDP1TSHR | |
| SCHEMBL8432720 | 0.82 | ALDH1A1 (0.34) | ALDH1A1ALOX15GAA | |
| SCHEMBL8535439 | 0.82 | EPHX2 (0.36) | EPHX2ALOX5ALDH1A1ALOX15TDP1 | |
| SCHEMBL13297927 | 0.81 | PAOX (0.33) | ALOX15 | |
| SCHEMBL9210174 | 0.80 | ALDH1A1 (0.33) | ALDH1A1ALOX15GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434079-B1 | N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives | ATOCHEM NORTH AMERICA (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5132387-A | Polyme bound | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1992-07-21 | — | — | US | disclosed |
| EP-0494639-A2 | Hindered amine light stabilizer hydrazides for stabilizing polyurethane, polyurea and polyurethane-polyurea polymers | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1992-07-15 | — | — | EP | disclosed |
| US-5043372-A | Light stabilizers for polyolefins; reacting hydrazine with bis(half ester-half amide) | ATOCHEM NORTH AMERICA, INC. (US) | 1991-08-27 | — | — | US | disclosed |
| EP-0434079-A1 | N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1991-06-26 | — | — | EP | disclosed |