SCHEMBL9206833

SCHEMBL9206833

CCOC(=O)CC(=O)N(CCCCCCN(C(=O)CC(=O)OCC)C1CC(C)(C)NC(C)(C)C1)C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.37
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
ALDH1A1 P00352 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
EPHX2 P34913 9/20 0.34
ALOX15 P16050 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.31
POLB P06746 2/20 0.30
MAPT P10636 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9205591 0.88 EPHX2 (0.36) KMT2AMEN1ALDH1A1NPSR1EPHX2
SCHEMBL9209250 0.87 EPHX2 (0.40) GAAALDH1A1EPHX2ALOX15
SCHEMBL9210243 0.87 EPHX2 (0.40) GAAALDH1A1EPHX2ALOX15
SCHEMBL8432720 0.85 ALDH1A1 (0.34) GAAKMT2AMEN1ALDH1A1NPSR1
SCHEMBL9210174 0.82 ALDH1A1 (0.33) GAAKMT2AMEN1ALDH1A1NPSR1
SCHEMBL10994774 0.81 ALDH1A1 (0.33) KMT2AMEN1ALDH1A1NPSR1L3MBTL1
SCHEMBL10990697 0.80 ALDH1A1 (0.35) GAAKMT2AMEN1ALDH1A1NPSR1
SCHEMBL9160814 0.79 PIN1 (0.35) GAAKMT2AMEN1ALDH1A1ALOX15
SCHEMBL9120612 0.79 ATM (0.33) GAAKMT2AMEN1ALOX15L3MBTL1
SCHEMBL13246441 0.78 ALOX15 (0.32) ALOX15POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434079-B1 N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives ATOCHEM NORTH AMERICA (US) 1995-09-20 EP disclosed
US-5132387-A Polyme bound ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-07-21 US disclosed
EP-0494639-A2 Hindered amine light stabilizer hydrazides for stabilizing polyurethane, polyurea and polyurethane-polyurea polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-07-15 EP disclosed
US-5043372-A Light stabilizers for polyolefins; reacting hydrazine with bis(half ester-half amide) ATOCHEM NORTH AMERICA, INC. (US) 1991-08-27 US disclosed
EP-0434079-A1 N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-06-26 EP disclosed