Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209250 | 0.94 | EPHX2 (0.40) | EPHX2CYP1A2ALOX5ALDH1A1USP2 | |
| SCHEMBL9210243 | 0.94 | EPHX2 (0.40) | EPHX2CYP1A2ALOX5ALDH1A1USP2 | |
| SCHEMBL9206833 | 0.88 | GAA (0.37) | EPHX2ALDH1A1ALOX15MEN1KMT2A | |
| SCHEMBL8432720 | 0.83 | ALDH1A1 (0.34) | SMN1; SMN2ALDH1A1ALOX15MEN1KMT2A | |
| SCHEMBL8535439 | 0.83 | EPHX2 (0.36) | EPHX2CYP1A2ALOX5ALDH1A1USP2 | |
| SCHEMBL8430751 | 0.82 | KDM5A (0.38) | EPHX2 | |
| SCHEMBL9210174 | 0.81 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1ALOX15MEN1KMT2A | |
| SCHEMBL10865852 | 0.81 | ALOX15 (0.32) | ALOX15 | |
| SCHEMBL10994774 | 0.80 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL536568 | 0.79 | KDM5A (0.35) | EPHX2ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434079-B1 | N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives | ATOCHEM NORTH AMERICA (US) | 1995-09-20 | — | — | EP | disclosed |
| EP-0494639-A2 | Hindered amine light stabilizer hydrazides for stabilizing polyurethane, polyurea and polyurethane-polyurea polymers | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1992-07-15 | — | — | EP | disclosed |
| US-5043372-A | Light stabilizers for polyolefins; reacting hydrazine with bis(half ester-half amide) | ATOCHEM NORTH AMERICA, INC. (US) | 1991-08-27 | — | — | US | disclosed |
| EP-0434079-A1 | N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1991-06-26 | — | — | EP | disclosed |