Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | SHMT2 | P34897 | 8/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10760459 | 0.80 | ALDH1A1 (0.72) | POLBKMT2AALDH1A1 | |
| SCHEMBL6210715 | 0.79 | TP53 (0.72) | LMNAPOLBSHMT2THRBTP53 | |
| SCHEMBL17792748 | 0.77 | SHMT2 (1.00) | LMNAPOLBSHMT2THRBTP53 | |
| SCHEMBL17792706 | 0.77 | SHMT2 (1.00) | LMNAPOLBSHMT2THRBTP53 | |
| SCHEMBL6213022 | 0.75 | THRB (0.81) | LMNAPOLBSHMT2THRBTP53 | |
| SCHEMBL219441 | 0.72 | POLB (0.48) | LMNAPOLBSHMT2THRBALDH1A1 | |
| SCHEMBL4984513 | 0.71 | POLB (0.67) | LMNAPOLBSHMT2THRBTP53 | |
| SCHEMBL6215163 | 0.71 | TP53 (1.00) | LMNAPOLBSHMT2THRBTP53 | |
| SCHEMBL6339434 | 0.71 | KMT2A (0.55) | LMNAPOLBTP53KMT2AALDH1A1 | |
| SCHEMBL3407130 | 0.70 | SHMT2 (0.56) | LMNAPOLBSHMT2THRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405976-B1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA CO (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5200407-A | Antisecretory agents | MEIJI SEIKA KABURHIKI KAISHA (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5141946-A | Antisecretory agents; acid resistance | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5079255-A | Nontoxic, acid stability | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0405976-A1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-01-02 | — | — | EP | disclosed |