SCHEMBL92104

SCHEMBL92104

CN1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(CCS(=O)(=O)O)C5=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 8/20 0.54
STAT3 P40763 1/20 0.51
HIF1A Q16665 1/20 0.51
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
RGS12 O14924 1/20 0.44
NPC1 O15118 1/20 0.44
LMNA P02545 1/20 0.44
PABPC1 P11940 1/20 0.44
HTT P42858 1/20 0.44
RECQL P46063 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
PIN1 Q13526 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32689773 1.00 TERT (0.54) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL13883925 0.89 TERT (0.48) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL14023201 0.87 KDM4E (0.55) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL24813700 0.85 STAT3 (0.57) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL14024117 0.82 KDM4E (0.46) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL16557130 0.82 STAT3 (0.55) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL16558636 0.82 STAT3 (0.55) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL12942839 0.79 TERT (0.49) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL9968962 0.79 TERT (0.56) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL9968958 0.79 TERT (0.56) TERTSTAT3HIF1AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8128848-B2 Diketopyrrolopyrrole pigment composition for use in color filters CLARIANT FINANCE (BVI) LIMITED (VG) 2012-03-06 US disclosed
US-8128848-B2 Diketopyrrolopyrrole pigment composition for use in color filters CLARIANT FINANCE (BVI) LIMITED (VG) 2012-03-06 US disclosed
EP-2205682-B1 DIKETOPYRROLOPYRROLE PIGMENT COMPOSITION FOR USE IN COLOR FILTERS CLARIANT FINANCE BVI LTD (VG) 2011-03-09 EP disclosed
US-20100219384-A1 Diketopyrrolopyrrole Pigment Composition For Use In Color Filters CLARIANT FINANCE (BVI) LIMITED (VG) 2010-09-02 US disclosed
US-20100219384-A1 Diketopyrrolopyrrole Pigment Composition For Use In Color Filters CLARIANT FINANCE (BVI) LIMITED (VG) 2010-09-02 US disclosed