Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3027067 | 0.83 | HPGD (0.36) | DDR1ALDH1A1APOBEC3G | |
| SCHEMBL16844673 | 0.83 | PTGS2 (0.51) | PTGS2HTR7CHRM4DDR1PDE5A | |
| SCHEMBL30548746 | 0.80 | PTGS2 (0.55) | PTGS2HTR7PDE5ASOAT1ALDH1A1 | |
| SCHEMBL10350653 | 0.80 | PTGS2 (0.55) | PTGS2HTR7PDE5ASOAT1ALDH1A1 | |
| SCHEMBL26942237 | 0.80 | APOBEC3G (0.57) | PTGS2HTR7CHRM4DDR1PDE5A | |
| SCHEMBL24779796 | 0.77 | PTGS2 (0.42) | PTGS2HTR7CHRM4DDR1PDE5A | |
| SCHEMBL2959162 | 0.75 | PTGS2 (0.47) | PTGS2HTR7CHRM4DDR1PDE5A | |
| SCHEMBL7464903 | 0.74 | PTGS2 (0.46) | PTGS2SOAT1ALDH1A1TLR8 | |
| SCHEMBL4801748 | 0.74 | CHRM2 (0.48) | HTR7CHRM4ALDH1A1APOBEC3G | |
| SCHEMBL19260908 | 0.73 | POLB (0.59) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650476-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-03 | — | — | EP | disclosed |