Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214894 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL593083 | 0.80 | HRH3 (0.48) | ALDH1A1HTTSIGMAR1KDM1ACYP2C19 | |
| SCHEMBL9208818 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5232155 | 0.77 | SIGMAR1 (0.57) | ALDH1A1HTTSIGMAR1KDM1ACYP2C19 | |
| SCHEMBL2026093 | 0.76 | HTT (0.66) | ALDH1A1HPGDSMN1; SMN2KDM4EHTT | |
| SCHEMBL9378269 | 0.76 | SIGMAR1 (0.51) | HTTSIGMAR1KDM1ACYP2C19TSHR | |
| SCHEMBL29289301 | 0.73 | SIGMAR1 (0.49) | HTTSIGMAR1KDM1ACYP2C19TSHR | |
| SCHEMBL5144954 | 0.71 | ALDH1A1 (0.51) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3781095 | 0.71 | CYP1A2 (0.49) | ALDH1A1NPC1RAB9AKDM4ESIGMAR1 | |
| SCHEMBL2585841 | 0.70 | ALDH1A1 (0.45) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492178-B1 | Naphthoic acid derivative | FUJIREBIO KK (JP) | 1995-10-04 | — | — | EP | disclosed |
| US-5324728-A | Lipoxygenase inhibiting antiallergens | FUJIREBIO INC. (JP) | 1994-06-28 | — | — | US | disclosed |
| EP-0492178-A2 | Naphthoic acid derivative | FUJIREBIO INC. (JP) | 1992-07-01 | — | — | EP | disclosed |