Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.59 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.59 |
| ▸ | GPR4 | P46093 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843709 | 0.88 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL13743046 | 0.85 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9563125 | 0.83 | AGTR1 (0.57) | AGTR1AGTR2GPR4 | |
| SCHEMBL14409680 | 0.83 | — | — | |
| SCHEMBL5421726 | 0.81 | — | — | |
| SCHEMBL8741166 | 0.81 | AGTR2 (0.61) | AGTR1AGTR2GPR4 | |
| SCHEMBL4320345 | 0.81 | — | — | |
| Methylamine SCHEMBL9307845 | 0.81 | — | — | |
| SCHEMBL5434268 | 0.80 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL9563137 | 0.79 | AGTR2 (0.57) | AGTR1AGTR2GPR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649424-A1 | DIOXCYCLOBUTENE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | Knoll AG (DE) | 1995-04-26 | — | — | EP | disclosed |