Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.57 |
| ▸ | GPR4 | P46093 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741166 | 0.86 | AGTR2 (0.61) | AGTR2AGTR1GPR4 | |
| SCHEMBL9139089 | 0.82 | GPR4 (0.51) | AGTR2AGTR1GPR4 | |
| SCHEMBL9137156 | 0.82 | GPR4 (0.53) | AGTR2AGTR1GPR4 | |
| SCHEMBL9563125 | 0.81 | AGTR1 (0.57) | AGTR2AGTR1GPR4 | |
| SCHEMBL8999434 | 0.80 | — | — | |
| SCHEMBL29486808 | 0.80 | AGTR1 (0.74) | AGTR2AGTR1GPR4 | |
| L-158809 SCHEMBL683357 | 0.80 | AGTR2 (0.71) | AGTR2AGTR1GPR4 | |
| L-158809 SCHEMBL7944169 | 0.79 | AGTR2 (0.70) | AGTR2AGTR1GPR4 | |
| SCHEMBL9210636 | 0.79 | AGTR1 (0.59) | AGTR2AGTR1GPR4 | |
| SCHEMBL9847826 | 0.79 | AGTR1 (0.62) | AGTR2AGTR1GPR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556789-A2 | Substituted biphenyl derivatives, therapeutic agents containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-08-25 | — | — | EP | claimed |
| EP-0556789-A2 | Substituted biphenyl derivatives, therapeutic agents containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-08-25 | — | — | EP | disclosed |