Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213200 | 0.86 | KDM4C (0.49) | PAMALDH1A1L3MBTL1MAOBMAPT | |
| SCHEMBL9213867 | 0.85 | PAM (0.54) | PAMALDH1A1MAOBMAPTSMN1; SMN2 | |
| SCHEMBL9212612 | 0.83 | KMT2A (0.56) | PAMALDH1A1MAOBMAPTSMN1; SMN2 | |
| SCHEMBL8828409 | 0.81 | PAM (0.58) | PAMALDH1A1L3MBTL1MAOBMAPT | |
| SCHEMBL8828415 | 0.81 | PAM (0.58) | PAMALDH1A1L3MBTL1MAOBMAPT | |
| SCHEMBL15106073 | 0.81 | MAPT (0.58) | ALDH1A1L3MBTL1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL15106075 | 0.81 | MAPT (0.58) | ALDH1A1L3MBTL1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9155176 | 0.76 | MAPT (0.45) | PAMALDH1A1L3MBTL1MAOBMAPT | |
| SCHEMBL9155171 | 0.76 | MAPT (0.45) | PAMALDH1A1L3MBTL1MAOBMAPT | |
| SCHEMBL9155185 | 0.76 | MAPT (0.45) | PAMALDH1A1L3MBTL1MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399358-B1 | Butenoic acid derivatives | EISAI CO LTD (JP) | 1995-03-08 | — | — | EP | disclosed |
| EP-0633248-A1 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0589491-A1 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1994-03-30 | — | — | EP | disclosed |
| EP-0399358-A2 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |