Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210792 | 0.85 | PAM (0.51) | PAMMAOBALDH1A1KMT2ARAB9A | |
| SCHEMBL8868330 | 0.84 | ALDH1A1 (0.51) | MAOBALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL8868345 | 0.84 | ALDH1A1 (0.51) | MAOBALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL8868335 | 0.84 | ALDH1A1 (0.51) | MAOBALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL8828409 | 0.84 | PAM (0.58) | PAMMAOBALDH1A1KMT2ANPC1 | |
| SCHEMBL8828415 | 0.84 | PAM (0.58) | PAMMAOBALDH1A1KMT2ANPC1 | |
| SCHEMBL7746675 | 0.79 | ALDH1A1 (0.53) | MAOBALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL7746671 | 0.79 | ALDH1A1 (0.53) | MAOBALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL9155176 | 0.78 | MAPT (0.45) | PAMMAOBALDH1A1KMT2ANPC1 | |
| SCHEMBL9155171 | 0.78 | MAPT (0.45) | PAMMAOBALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399358-B1 | Butenoic acid derivatives | EISAI CO LTD (JP) | 1995-03-08 | — | — | EP | disclosed |
| EP-0633248-A1 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0589491-A1 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1994-03-30 | — | — | EP | disclosed |