Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213200 | 0.89 | KDM4C (0.49) | KMT2AMAPTALOX12GAAALDH1A1 | |
| SCHEMBL9210792 | 0.83 | PAM (0.51) | KMT2AMAPTGAACYP1A2CYP2C9 | |
| SCHEMBL8828415 | 0.77 | PAM (0.58) | KMT2AMAPTGAAALDH1A1PAM | |
| SCHEMBL8828409 | 0.77 | PAM (0.58) | KMT2AMAPTGAAALDH1A1PAM | |
| SCHEMBL7151984 | 0.75 | CYP1A2 (0.68) | KMT2AMAPTALOX12GAACYP1A2 | |
| SCHEMBL9213867 | 0.75 | PAM (0.54) | KMT2AMAPTALDH1A1PAMLMNA | |
| SCHEMBL5458013 | 0.73 | KMT2A (1.00) | KMT2AMAPTALOX12GAACYP1A2 | |
| SCHEMBL25517525 | 0.72 | CYP1A2 (0.72) | KMT2AMAPTALOX12GAACYP1A2 | |
| SCHEMBL5455860 | 0.72 | CYP1A2 (0.72) | KMT2AMAPTALOX12GAACYP1A2 | |
| SCHEMBL9230563 | 0.72 | PAM (0.41) | KMT2AMAPTALDH1A1PAMMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399358-B1 | Butenoic acid derivatives | EISAI CO LTD (JP) | 1995-03-08 | — | — | EP | disclosed |
| EP-0633248-A1 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0589491-A1 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1994-03-30 | — | — | EP | disclosed |
| EP-0399358-A2 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |