Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211133 | 0.90 | MAPK14 (0.58) | MAPK14 | |
| SCHEMBL9208497 | 0.90 | ACAT1 (0.54) | ACAT1SOAT1 | |
| Hydrochloric Acid SCHEMBL9212101 | 0.89 | ACAT1 (0.53) | KDM4EACAT1SOAT1 | |
| SCHEMBL9209108 | 0.88 | ACAT1 (0.57) | ACAT1SOAT1 | |
| SCHEMBL9213144 | 0.87 | ACAT1 (0.59) | ACAT1SOAT1 | |
| SCHEMBL9211240 | 0.87 | ACAT1 (0.59) | ACAT1SOAT1 | |
| Maleic Acid SCHEMBL9215913 | 0.83 | KDM4E (0.48) | KDM4EACAT1SOAT1 | |
| SCHEMBL9213622 | 0.76 | KDM4E (0.48) | KDM4E | |
| SCHEMBL9213632 | 0.76 | KDM4E (0.48) | KDM4E | |
| SCHEMBL9209606 | 0.76 | ACAT1 (0.53) | ACAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505468-B1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS ACYL COENZYME-A INHIBITORS | RHONE POULENC SANTE (FR) | 1995-04-26 | — | — | EP | claimed |
| EP-0505468-B1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS ACYL COENZYME-A INHIBITORS | RHONE POULENC SANTE (FR) | 1995-04-26 | — | — | EP | disclosed |
| EP-0505468-A1 | IMIDAZOLES. | RHONE POULENC SANTE (FR) | 1992-09-30 | — | — | EP | disclosed |
| WO-1991009021-A1 | IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1991-06-27 | — | — | WO | disclosed |