Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.58 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211101 | 0.90 | KDM4E (0.46) | MAPK14 | |
| SCHEMBL9208497 | 0.89 | ACAT1 (0.54) | — | |
| Hydrochloric Acid SCHEMBL9212101 | 0.88 | ACAT1 (0.53) | — | |
| SCHEMBL9209108 | 0.87 | ACAT1 (0.57) | — | |
| SCHEMBL9211240 | 0.86 | ACAT1 (0.59) | — | |
| SCHEMBL9213144 | 0.86 | ACAT1 (0.59) | — | |
| SCHEMBL11172467 | 0.83 | MAPK14 (0.74) | MAPK14MAPK13MAPK12MAPK11 | |
| Bromide SCHEMBL11188991 | 0.82 | MAPK14 (0.72) | MAPK14MAPK13MAPK12MAPK11 | |
| Maleic Acid SCHEMBL9215913 | 0.82 | KDM4E (0.48) | — | |
| SCHEMBL11176876 | 0.81 | MAPK14 (0.74) | MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505468-B1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS ACYL COENZYME-A INHIBITORS | RHONE POULENC SANTE (FR) | 1995-04-26 | — | — | EP | claimed |
| EP-0505468-B1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS ACYL COENZYME-A INHIBITORS | RHONE POULENC SANTE (FR) | 1995-04-26 | — | — | EP | disclosed |
| WO-1991009021-A1 | IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1991-06-27 | — | — | WO | disclosed |