Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 2/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208725 | 0.86 | MEN1 (0.67) | STAT3KMT2AMEN1KCNH2CACNA1F | |
| SCHEMBL9208720 | 0.85 | ADRB2 (0.57) | STAT3KMT2AADRB2KCNH2POLB | |
| SCHEMBL10777266 | 0.85 | MEN1 (0.55) | STAT3KMT2AMEN1TSHRCASP1 | |
| SCHEMBL1345146 | 0.84 | STAT3 (0.65) | STAT3KMT2AMEN1TSHRCASP1 | |
| SCHEMBL9208068 | 0.80 | ADRB2 (0.55) | STAT3KMT2AADRB2KCNH2POLB | |
| SCHEMBL9720451 | 0.80 | STAT3 (0.54) | STAT3KMT2AMEN1TSHRCASP1 | |
| SCHEMBL10679793 | 0.80 | MEN1 (0.70) | STAT3KMT2AMEN1KCNH2CACNA1F | |
| SCHEMBL9585893 | 0.80 | STAT3 (0.54) | STAT3KMT2AMEN1TSHRCASP1 | |
| SCHEMBL10339785 | 0.79 | STAT3 (0.53) | STAT3KMT2AMEN1TSHRCASP1 | |
| SCHEMBL9267912 | 0.79 | STAT3 (0.61) | STAT3KMT2AMEN1TSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390215-B1 | Quinolone derivatives and salts thereof, preparation process es thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KK (JP) | 1995-06-07 | — | — | EP | disclosed |
| US-5153203-A | QUINOLONE DERIVATIVES AND SALTS THEREOF, PREPARATION PROCESSES THEREOF, AND ANTIBACTERIAL AGENTS CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0390215-A2 | Quinolone derivatives and salts thereof, preparation process es thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1990-10-03 | — | — | EP | disclosed |