Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | UCHL3 | P15374 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397637 | 0.79 | IDO1 (0.50) | IDO1CNR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9204871 | 0.78 | DNM1 (0.46) | SMN1; SMN2CYP3A4TP53CYP2D6CYP2C9 | |
| SCHEMBL9210794 | 0.78 | DNM1 (0.46) | SMN1; SMN2CYP3A4TP53CYP2D6CYP2C9 | |
| SCHEMBL10821498 | 0.78 | DNM1 (0.46) | SMN1; SMN2CYP3A4TP53CYP2D6CYP2C9 | |
| SCHEMBL9205311 | 0.78 | DNM1 (0.46) | SMN1; SMN2CYP3A4TP53CYP2D6CYP2C9 | |
| SCHEMBL9209833 | 0.78 | DNM1 (0.46) | SMN1; SMN2CYP3A4TP53CYP2D6CYP2C9 | |
| SCHEMBL9214128 | 0.78 | DNM1 (0.46) | SMN1; SMN2CYP3A4TP53CYP2D6CYP2C9 | |
| SCHEMBL617341 | 0.78 | DNM1 (0.46) | SMN1; SMN2CYP3A4TP53CYP2D6CYP2C9 | |
| SCHEMBL9206119 | 0.76 | ESR1 (0.41) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL9819726 | 0.76 | SIGMAR1 (0.44) | SMN1; SMN2CYP3A4TP53CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |