Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.42 |
| ▸ | CETP | P11597 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204871 | 1.00 | DNM1 (0.46) | DNM1MEN1KMT2AEPHX2TP53 | |
| SCHEMBL9205311 | 1.00 | DNM1 (0.46) | DNM1MEN1KMT2AEPHX2TP53 | |
| SCHEMBL9214128 | 1.00 | DNM1 (0.46) | DNM1MEN1KMT2AEPHX2TP53 | |
| SCHEMBL9209833 | 1.00 | DNM1 (0.46) | DNM1MEN1KMT2AEPHX2TP53 | |
| SCHEMBL9210794 | 1.00 | DNM1 (0.46) | DNM1MEN1KMT2AEPHX2TP53 | |
| SCHEMBL10821498 | 1.00 | DNM1 (0.46) | DNM1MEN1KMT2AEPHX2TP53 | |
| SCHEMBL9819726 | 0.98 | SIGMAR1 (0.44) | DNM1MEN1KMT2AEPHX2TP53 | |
| SCHEMBL2776492 | 0.92 | TP53 (0.42) | DNM1MEN1KMT2AEPHX2TP53 | |
| SCHEMBL9819966 | 0.84 | KCNH2 (0.61) | TP53KCNH2SIGMAR1CYP3A4 | |
| SCHEMBL9212818 | 0.84 | SIGMAR1 (0.52) | DNM1MEN1KMT2AEPHX2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904360-B1 | NOVEL TETRAARYLBORATE COMPOUND, CATALYST COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFIN BY USING SAME | SABIC SK NEXLENE COMPANY PTE LTD (SG) | 2024-07-03 | — | — | EP | disclosed |
| CN-113677686-B | Novel tetraarylborate compounds, catalyst compositions comprising the same, and process for preparing ethylene homopolymers or copolymers of ethylene and alpha-olefins by using the same | 沙特基础工业爱思开NEXLENE私人有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111148748-B | Novel indene-based transition metal compound, transition metal catalyst composition comprising the same, and method for preparing ethylene homopolymer or copolymer of ethylene and alpha-olefin by using the same | 沙特基础工业爱思开NEXLENE私人有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-113677686-A | Novel tetraarylborate compound, catalyst composition comprising the same, and method for preparing ethylene homopolymer or copolymer of ethylene and alpha-olefin by using the same | 沙特基础工业爱思开NEXLENE私人有限公司 | 2021-11-19 | — | — | CN | disclosed |
| EP-3904360-A1 | NOVEL TETRAARYLBORATE COMPOUND, CATALYST COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFIN BY USING SAME | SABIC SK Nexlene Company Pte. Ltd. (SG) | 2021-11-03 | — | — | EP | disclosed |
| US-10919992-B2 | Indene-based transition metal compound, transition metal catalyst composition comprising same, and method for preparing ethylene homopolymer or copolymer of ethylene and alpha-olefin by using same | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2021-02-16 | — | — | US | disclosed |
| US-20200262943-A1 | NOVEL INDENE-BASED TRANSITION METAL COMPOUND, TRANSITION METAL CATALYST COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMER OR COPOLYMER OF ETHYLENE AND ALPHA-OLEFIN BY USING SAME | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2020-08-20 | — | — | US | disclosed |
| EP-3689884-A1 | NOVEL INDENE-BASED TRANSITION METAL COMPOUND, TRANSITION METAL CATALYST COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMER OR COPOLYMER OF ETHYLENE AND -OLEFIN BY USING SAME | Sabic Sk Nexlene Company Pte. Ltd. (SG) | 2020-08-05 | — | — | EP | disclosed |
| CN-111148748-A | Novel indene-based transition metal compound, transition metal catalyst composition comprising the same, and method for preparing ethylene homopolymer or copolymer of ethylene and α -olefin by using the same | 沙特基础工业爱思开NEXLENE私人有限公司 | 2020-05-12 | — | — | CN | disclosed |
| US-10487163-B2 | Cyclopenta[b]fluorenyl transition metal compound, catalyst composition containing the same, and method of preparing ethylene homopolymer or copolymer of ethylene and alpha-olefin using the same | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2019-11-26 | — | — | US | disclosed |
| US-5624935-A | ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS OR ANTILIPEMIC AGENTS | SANKYO COMPANY, LIMITED | 1997-04-29 | — | — | US | disclosed |
| EP-0676398-A2 | Heterocyclic compounds having anti-diabetic activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0167817-B1 | 8-Alkylthio-2-piperazino-pyrimido[5,4-d]pyrimidines, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1989-09-20 | — | — | EP | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |
| US-4714698-A | ANTITUMOR, ANTICOAGULANT | DR. KARL THOMAE GMBH (DE) | 1987-12-22 | — | — | US | disclosed |
| EP-0167817-A1 | 8-Alkylthio-2-piperazino-pyrimido[5,4-d]pyrimidines, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1986-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10919992-B2 | Indene-based transition metal compound, transition metal catalyst composition comprising same, and method for preparing ethylene homopolymer or copolymer of ethylene and alpha-olefin by using same | ETFB, EMC2, ICMT | DNM1 188/4885MEN1 392/4885KMT2A 2884/4885 |
| US-10487163-B2 | Cyclopenta[b]fluorenyl transition metal compound, catalyst composition containing the same, and method of preparing ethylene homopolymer or copolymer of ethylene and alpha-olefin using the same | ETFB, ETFA, NOTUM | DNM1 225/4885MEN1 1587/4885KMT2A 3046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.