Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 2/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 4/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875626 | 0.95 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9705668 | 0.89 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9208044 | 0.88 | NR1I2 (0.50) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9876491 | 0.85 | ICMT (0.44) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9436214 | 0.84 | NR1I2 (0.43) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9862969 | 0.83 | ICMT (0.44) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL8128286 | 0.82 | NR1I2 (0.55) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9436179 | 0.81 | CYP1A2 (0.46) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL11034112 | 0.81 | CYP1A2 (0.46) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9666814 | 0.81 | CYP1A2 (0.46) | NR1I2CYP3A4CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413289-B1 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC (US) | 1995-02-01 | — | — | EP | disclosed |
| EP-0207453-B1 | Heterocyclic substituted-phenoxyalkyl-isoxazoles and-furans, their preparation and use as antiviral agents | STERLING WINTHROP INC (US) | 1994-06-22 | — | — | EP | disclosed |
| US-5175178-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING DRUG INC. (US) | 1992-12-29 | — | — | US | disclosed |
| US-5110821-A | Picornavirus | STERLING DRUG INC. (US) | 1992-05-05 | — | — | US | disclosed |
| US-5051437-A | Treatment of rhinovirus or picornaviruses | STERLING DRUG INC. (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0413289-A2 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1991-02-20 | — | — | EP | disclosed |
| US-4945164-A | 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof | STERLING DRUG INC. (US) | 1990-07-31 | — | — | US | disclosed |
| US-4942241-A | PICORNAVIRUS INCLUDING RHINOVIRUS | STERLING DRUG INC. (US) | 1990-07-17 | — | — | US | disclosed |
| US-4857539-A | Heterocyclic substituted-phenoxyalkylisoxazoles as antiviral useful agents | STERLING DRUG INC. (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0207453-A2 | Heterocyclic substituted-phenoxyalkyl-isoxazoles and-furans, their preparation and use as antiviral agents | STERLING WINTHROP INC. (US) | 1987-01-07 | — | — | EP | disclosed |