Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211432 | 0.89 | NR1I2 (0.41) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL8875626 | 0.85 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9863089 | 0.81 | MRGPRX4 (0.42) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9705898 | 0.81 | NR1I2 (0.46) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL9208044 | 0.80 | NR1I2 (0.50) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9876491 | 0.78 | ICMT (0.44) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9705747 | 0.77 | NR1I2 (0.43) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8136926 | 0.77 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9862969 | 0.76 | ICMT (0.44) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL8134990 | 0.76 | NR1I2 (0.47) | NR1I2CYP3A4CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207454-B1 | ISOXAZOLE AND FURAN DERIVATIVES, THEIR PREPARATION AND USE AS ANTIVIRAL AGENTS | STERLING WINTHROP INC. (US) | 1992-09-09 | — | — | EP | disclosed |
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0207454-A2 | Isoxazole and furan derivatives, their preparation and use as antiviral agents | STERLING WINTHROP INC. (US) | 1987-01-07 | — | — | EP | disclosed |