Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 6/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215312 | 0.93 | MAPT (0.34) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL9275150 | 0.92 | MEN1 (0.37) | MEN1KMT2AL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL9216433 | 0.86 | MTNR1A (0.33) | MTNR1AMTNR1B | |
| SCHEMBL9215417 | 0.86 | MEN1 (0.36) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL9219323 | 0.84 | PPARG (0.36) | MEN1KMT2A | |
| SCHEMBL9219849 | 0.78 | MTNR1A (0.35) | MAPTMTNR1AMTNR1B | |
| SCHEMBL9212152 | 0.77 | PPARG (0.34) | MEN1KMT2AMAPT | |
| SCHEMBL9213079 | 0.77 | FFAR1 (0.37) | KMT2AMAPT | |
| SCHEMBL9218525 | 0.73 | SMN1; SMN2 (0.48) | NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL9218845 | 0.73 | PPARG (0.43) | NPC1RAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | claimed |