SCHEMBL921165

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL920505	0.91	HPGD (0.52)	ALDH1A1HPGDKDM4EUSP2ADORA2A
	SCHEMBL921775	0.90	KDM4E (0.48)	ALDH1A1HPGDKDM4EUSP2MMP13
	SCHEMBL920788	0.90	HPGD (0.43)	ALDH1A1HPGDADORA2AMAPK1CARM1
	SCHEMBL919303	0.89	PPARG (0.47)	ALDH1A1HPGDKDM4EUSP2MMP13
	SCHEMBL919958	0.89	HPGD (0.48)	ALDH1A1HPGDKDM4EUSP2MMP13
	SCHEMBL919945	0.89	HPGD (0.48)	ALDH1A1HPGDKDM4EUSP2MMP13
	SCHEMBL920865	0.89	HPGD (0.48)	ALDH1A1HPGDKDM4EUSP2MMP13
	SCHEMBL920127	0.89	KDM4E (0.47)	ALDH1A1HPGDKDM4EUSP2ADORA2A
	SCHEMBL920645	0.89	KDM4E (0.53)	ALDH1A1HPGDKDM4EUSP2MMP13
	SCHEMBL920766	0.89	KDM4E (0.46)	ALDH1A1HPGDKDM4EUSP2MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.