SCHEMBL920127

SCHEMBL920127

COCc1ccc(C(=O)NCc2cccc(Oc3ccc(F)cc3)c2)c(N)n1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
MMP13 P45452 1/20 0.45
TP53 P04637 2/20 0.44
PPARG P37231 5/20 0.43
PPARA Q07869 5/20 0.43
PPARD Q03181 4/20 0.43
ROCK2 O75116 1/20 0.43
ROCK1 Q13464 1/20 0.43
MAPK14 Q16539 1/20 0.42
ADORA2A P29274 1/20 0.42
LIPG Q9Y5X9 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921647 0.93 HPGD (0.47) KDM4EUSP2ALDH1A1HPGDMMP13
SCHEMBL919552 0.92 HPGD (0.53) KDM4EUSP2ALDH1A1HPGDMMP13
SCHEMBL920645 0.92 KDM4E (0.53) KDM4EUSP2ALDH1A1HPGDMMP13
SCHEMBL920812 0.91 MMP13 (0.56) KDM4EUSP2ALDH1A1HPGDMMP13
SCHEMBL919566 0.91 PPARG (0.48) KDM4EUSP2ALDH1A1HPGDMMP13
SCHEMBL922486 0.91 HPGD (0.47) KDM4EUSP2ALDH1A1HPGDMMP13
SCHEMBL920104 0.91 HPGD (0.47) KDM4EUSP2ALDH1A1HPGDMMP13
SCHEMBL920083 0.91 HTR2C (0.45) KDM4EUSP2ALDH1A1HPGDTP53
SCHEMBL920779 0.90 LIPG (0.51) PPARGPPARAPPARDMAPK14LIPG
SCHEMBL920735 0.90 PPARG (0.52) KDM4EUSP2ALDH1A1HPGDMMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 KDM4E 3657/4885USP2 3233/4885ALDH1A1 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.