Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 5/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1138510 | 0.98 | FAAH (0.50) | GGPS1FAAHTRPV1SOAT1CYP1A2 | |
| Hydrochloric Acid SCHEMBL6895373 | 0.96 | FAAH (0.48) | GGPS1FAAHTRPV1SOAT1CYP1A2 | |
| Hydrochloric Acid SCHEMBL6893417 | 0.84 | ALDH1A1 (0.47) | FAAHTRPV1SOAT1CYP1A2CYP2C19 | |
| SCHEMBL10495290 | 0.83 | FAAH (0.48) | GGPS1FAAHTRPV1SOAT1CYP1A2 | |
| SCHEMBL165447 | 0.80 | FAAH (0.50) | FAAHTRPV1SOAT1CYP1A2CYP2C19 | |
| SCHEMBL9211167 | 0.80 | FAAH (0.50) | FAAHTRPV1SOAT1CYP1A2CYP2C19 | |
| SCHEMBL9202958 | 0.80 | FAAH (0.50) | FAAHTRPV1SOAT1CYP1A2CYP2C19 | |
| SCHEMBL9210560 | 0.80 | FAAH (0.50) | FAAHTRPV1SOAT1CYP1A2CYP2C19 | |
| SCHEMBL9211940 | 0.80 | FAAH (0.50) | FAAHTRPV1SOAT1CYP1A2CYP2C19 | |
| SCHEMBL21054942 | 0.79 | FAAH (0.54) | GGPS1FAAHTRPV1SOAT1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |