Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9211784 | 0.99 | CFTR (0.43) | CFTRGOPCEPHX2CYP2C9CYP2C19 | |
| SCHEMBL9208912 | 0.84 | CYP2C9 (0.51) | EPHX2CYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL9211726 | 0.84 | EPHX2 (0.49) | EPHX2CYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9218009 | 0.83 | CYP2C9 (0.50) | EPHX2CYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9218721 | 0.83 | EPHX2 (0.48) | EPHX2CYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL9215260 | 0.82 | EPHX2 (0.63) | EPHX2CYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL9211594 | 0.78 | KEAP1 (0.52) | EPHX2CYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL9214502 | 0.76 | KMT2A (0.61) | EPHX2CYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL9214627 | 0.75 | LMNA (0.42) | EPHX2CYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL9212201 | 0.75 | S1PR3 (0.47) | CFTRGOPCEPHX2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388528-B1 | Carboximidamide derivatives | KIRIN BREWERY (JP) | 1995-09-27 | — | — | EP | claimed |
| EP-0388528-A2 | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1990-09-26 | — | — | EP | claimed |
| EP-0388528-B1 | Carboximidamide derivatives | KIRIN BREWERY (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-5272164-A | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-12-21 | — | — | US | disclosed |
| US-5223508-A | Hypotensive agents, vasodilators | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-06-29 | — | — | US | disclosed |
| US-5166347-A | Hypotensive agents, cardiovascular disorders, antiischemic agents and anticoagulants | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-11-24 | — | — | US | disclosed |