Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436016 | 0.85 | HDAC3 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL158220 | 0.83 | HDAC3 (0.78) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7434407 | 0.83 | GAA (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27804343 | 0.82 | CA12 (0.55) | HDAC3GAAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8703043 | 0.81 | LMNA (0.51) | GAASMN1; SMN2LMNA | |
| SCHEMBL2918702 | 0.80 | GAA (0.64) | GAAKMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL7328495 | 0.79 | CTSK (0.50) | HDAC3HDAC1HDAC2NCOR2GAA | |
| SCHEMBL7769202 | 0.79 | NPC1 (0.50) | GAAMAPTSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL7345362 | 0.79 | HDAC3 (0.57) | HDAC3HDAC1HDAC2HDAC11HDAC8 | |
| SCHEMBL3824791 | 0.78 | HDAC3 (0.62) | HDAC3HDAC2HDAC8HDAC6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655055-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-05-31 | — | — | EP | disclosed |