Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KIT | P10721 | 4/20 | 0.42 |
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3004279 | 0.89 | NQO2 (0.45) | SMN1; SMN2KITKDRKDM4ENQO2 | |
| SCHEMBL1947459 | 0.87 | CA12 (0.56) | F9KITKDRMAPK14AURKB | |
| SCHEMBL7902665 | 0.85 | CA12 (0.50) | F9SMN1; SMN2MAPK14KDM4ELCK | |
| SCHEMBL22424604 | 0.82 | F9 (0.47) | F9KITKDRMAPK14LCK | |
| SCHEMBL12545753 | 0.82 | RAB9A (0.56) | F9SMN1; SMN2MAPK14KDM4ENPC1 | |
| SCHEMBL7904187 | 0.82 | CYP3A4 (0.47) | F9SMN1; SMN2KDM4ELCKCSF1R | |
| SCHEMBL6089216 | 0.77 | MAPT (0.51) | SMN1; SMN2MAPK14KDM4ELCKNPC1 | |
| SCHEMBL29652456 | 0.77 | MAPT (0.51) | SMN1; SMN2MAPK14KDM4ELCKNPC1 | |
| SCHEMBL22130230 | 0.76 | MAP4K4 (0.52) | KITKDRFLT3 | |
| Hydrochloric Acid SCHEMBL6089209 | 0.75 | MAPT (0.50) | SMN1; SMN2MAPK14KDM4ELCKNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669920-A4 | SUBSTITUTED 3-(AMINOALKYLAMINO)-1,2-BENZISOXAZOLES AND RELATED COMPOUNDS. | HOECHST ROUSSEL PHARMA (US) | 1995-10-25 | — | — | EP | disclosed |
| EP-0669920-A1 | SUBSTITUTED 3-(AMINOALKYLAMINO)-1,2-BENZISOXAZOLES AND RELATED COMPOUNDS | HOECHST MARION ROUSSEL, Inc. (US) | 1995-09-06 | — | — | EP | disclosed |