Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | F9 | P00740 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902665 | 0.84 | CA12 (0.50) | RAB9AF9ALDH1A1NPC1MEN1 | |
| SCHEMBL9212282 | 0.82 | F9 (0.45) | RAB9AF9ALDH1A1NPC1KDM4E | |
| SCHEMBL12545753 | 0.81 | RAB9A (0.56) | GAARAB9AF9TSHRALDH1A1 | |
| SCHEMBL21929348 | 0.79 | KDM4E (0.47) | POLBF9ALDH1A1KDM4ELCK | |
| SCHEMBL1947459 | 0.77 | CA12 (0.56) | F9MAP4K4CA12CA1CA9 | |
| SCHEMBL22424604 | 0.75 | F9 (0.47) | F9LCKCSF1R | |
| SCHEMBL20229888 | 0.74 | POLB (0.49) | POLBRAB9AALDH1A1NR4A1NPC1 | |
| SCHEMBL6689551 | 0.71 | NR3C1 (0.52) | CYP3A4POLBGAARAB9AALDH1A1 | |
| SCHEMBL3004279 | 0.70 | NQO2 (0.45) | KDM4ESMN1; SMN2 | |
| SCHEMBL23175956 | 0.70 | F9 (0.45) | GAARAB9AF9ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |