Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
| ▸ | QDPR | P09417 | 3/20 | 0.37 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246723 | 0.89 | SIGMAR1 (0.50) | SIGMAR1HTR2CQDPRHRH3 | |
| SCHEMBL21361657 | 0.83 | SIGMAR1 (0.52) | SIGMAR1HTR2CQDPRHRH3 | |
| SCHEMBL2105114 | 0.79 | TYMP (0.41) | TYMPELANEJAK2JAK1JAK3 | |
| SCHEMBL3502363 | 0.79 | TYMP (0.41) | TYMPELANEJAK2JAK1JAK3 | |
| SCHEMBL18244172 | 0.79 | TYMP (0.41) | TYMPELANEJAK2JAK1JAK3 | |
| SCHEMBL18244171 | 0.79 | TYMP (0.41) | TYMPELANEJAK2JAK1JAK3 | |
| SCHEMBL3233362 | 0.79 | TYMP (0.41) | TYMPELANEJAK2JAK1JAK3 | |
| SCHEMBL3233355 | 0.79 | TYMP (0.41) | TYMPELANEJAK2JAK1JAK3 | |
| SCHEMBL21057468 | 0.79 | TYMP (0.41) | TYMPELANEJAK2JAK1JAK3 | |
| SCHEMBL11201526 | 0.79 | TYMP (0.41) | TYMPELANEJAK2JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379416-B1 | Azabicycloheptene derivatives and their salts, process for their preparation, their use as medicaments and compositions containing them | ROUSSEL UCLAF (FR) | 1995-03-08 | — | — | EP | claimed |
| EP-0379416-A2 | Azabicycloheptene derivatives and their salts, process for their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1990-07-25 | — | — | EP | claimed |
| EP-0379416-B1 | Azabicycloheptene derivatives and their salts, process for their preparation, their use as medicaments and compositions containing them | ROUSSEL UCLAF (FR) | 1995-03-08 | — | — | EP | disclosed |
| EP-0379416-B1 | Azabicycloheptene derivatives and their salts, process for their preparation, their use as medicaments and compositions containing them | ROUSSEL UCLAF (FR) | 1995-03-08 | — | — | EP | disclosed |
| EP-0379416-A3 | AZABICYCLOHEPTENE DERIVATIVES AND THEIR SALTS, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1991-09-18 | — | — | EP | disclosed |
| EP-0379416-A2 | Azabicycloheptene derivatives and their salts, process for their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1990-07-25 | — | — | EP | disclosed |
| EP-0379416-A2 | Azabicycloheptene derivatives and their salts, process for their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1990-07-25 | — | — | EP | disclosed |