Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216023 | 0.91 | L3MBTL1 (0.54) | NAAAHPGDHTTALDH1A1TSHR | |
| SCHEMBL9219857 | 0.90 | NAAA (0.48) | NAAAHPGDALDH1A1TSHRUSP2 | |
| SCHEMBL9216814 | 0.89 | NAAA (0.50) | NAAAALOX15ASAH1HPGDEPHX1 | |
| SCHEMBL9220347 | 0.88 | NAAA (0.49) | NAAAALOX15ASAH1HPGDEPHX1 | |
| SCHEMBL9222019 | 0.88 | NAAA (0.46) | NAAAALOX15HPGDALDH1A1 | |
| SCHEMBL9220885 | 0.88 | EPHX1 (0.48) | NAAAALOX15HPGDEPHX1ALDH1A1 | |
| SCHEMBL9218746 | 0.87 | NAAA (0.48) | NAAAALOX15EPHX1ALDH1A1 | |
| SCHEMBL9217584 | 0.85 | NAAA (0.46) | NAAAALOX15ASAH1HPGDEPHX1 | |
| SCHEMBL9215701 | 0.85 | NAAA (0.45) | NAAAALOX15HPGDHTTALDH1A1 | |
| SCHEMBL9210126 | 0.84 | NAAA (0.49) | NAAAASAH1HPGDEPHX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| CN-1067886-A | New urea derivatives, their preparation method and pharmaceutical composition thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-01-13 | — | — | CN | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |