Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220885 | 0.88 | EPHX1 (0.48) | NAAAHPGDMAPK1ALOX15ALDH1A1 | |
| SCHEMBL9219857 | 0.88 | NAAA (0.48) | NAAAHPGDCNR1TSHRUSP2 | |
| SCHEMBL9212475 | 0.85 | NAAA (0.56) | NAAAHPGDHTTTSHRALOX15 | |
| SCHEMBL9216023 | 0.84 | L3MBTL1 (0.54) | NAAAHPGDHTTTSHRMAPK1 | |
| SCHEMBL9222019 | 0.83 | NAAA (0.46) | NAAAHPGDMAPK1ALOX15ALDH1A1 | |
| SCHEMBL9219000 | 0.83 | HPGD (0.49) | NAAAHPGDHTTPTGS2TSHR | |
| SCHEMBL9215682 | 0.83 | HDAC1 (0.47) | NAAANPC1RAB9AHPGDCNR1 | |
| SCHEMBL9218746 | 0.80 | NAAA (0.48) | NAAACNR1ALOX15ALDH1A1 | |
| SCHEMBL9216814 | 0.80 | NAAA (0.50) | NAAAHPGDHTTPTGS2ALOX15 | |
| SCHEMBL9219551 | 0.77 | L3MBTL1 (0.46) | HPGDCNR1TSHRALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |