Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 6/20 | 0.49 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233969 | 0.81 | BRD2 (0.52) | TYMSALDH1A1LMNATHRBTSHR | |
| SCHEMBL11884883 | 0.78 | TYMS (0.60) | TYMSALDH1A1LMNATHRBTSHR | |
| SCHEMBL9215071 | 0.72 | KDM4E (0.68) | ALDH1A1LMNA | |
| SCHEMBL9229976 | 0.71 | TYMS (0.52) | TYMSALDH1A1LMNATHRBTSHR | |
| SCHEMBL9674593 | 0.70 | KDM4E (0.55) | — | |
| SCHEMBL9675878 | 0.70 | KDM4E (0.55) | ACAT1SOAT1ALDH1A1LMNA | |
| SCHEMBL9232601 | 0.70 | TYMS (0.62) | TYMSALDH1A1LMNATHRBTSHR | |
| SCHEMBL18106939 | 0.70 | KDM4E (0.64) | ALDH1A1LMNAPTGS1PTGS2 | |
| SCHEMBL9211661 | 0.70 | ACAT1 (0.71) | ACAT1SOAT1 | |
| SCHEMBL9215059 | 0.70 | KDM4E (0.64) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510036-B1 | 2-SUBSTITUTED 4,5-DIPHENYL-IMIDAZOLES | RHONE POULENC RORER SA (FR) | 1995-04-19 | — | — | EP | disclosed |
| EP-0510036-A1 | 2-SUBSTITUTED 4,5-DIPHENYL-IMIDAZOLES. | RHONE POULENC RORER SA (FR) | 1992-10-28 | — | — | EP | disclosed |
| WO-1991010662-A1 | 2-SUBSTITUTED 4,5-DIPHENYL-IMIDAZOLES | RHONE-POULENC RORER S.A. (FR) | 1991-07-25 | — | — | WO | disclosed |