SCHEMBL9212487

SCHEMBL9212487

C#CCOC(=S)C(C)Oc1ccc(Oc2ncc(Cl)cc2Cl)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.57
LMNA P02545 2/20 0.51
CYP2C9 P11712 1/20 0.51
TSHR P16473 1/20 0.51
APEX1 P27695 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
MAPK1 P28482 1/20 0.49
LIPE Q05469 4/20 0.43
BCHE P06276 1/20 0.42
ACACB O00763 1/20 0.37
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
GAA P10253 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
IP6K1 Q92551 1/20 0.35
IP6K3 Q96PC2 1/20 0.35
IP6K2 Q9UHH9 1/20 0.35
FFAR1 O14842 1/20 0.35
SCN9A Q15858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8332894 0.88 L3MBTL1 (0.69) L3MBTL1LMNACYP2C9TSHRAPEX1
SCHEMBL30939017 0.88 L3MBTL1 (0.69) L3MBTL1LMNACYP2C9TSHRAPEX1
SCHEMBL10014385 0.81 L3MBTL1 (0.56) L3MBTL1LMNACYP2C9TSHRAPEX1
Clodinafop Propargyl SCHEMBL29375181 0.79 L3MBTL1 (0.57) L3MBTL1LMNACYP2C9TSHRAPEX1
Clodinafop Propargyl SCHEMBL10014176 0.79 L3MBTL1 (0.57) L3MBTL1LMNACYP2C9TSHRAPEX1
Clodinafop Propargyl SCHEMBL63885 0.79 L3MBTL1 (0.57) L3MBTL1LMNACYP2C9TSHRAPEX1
Clodinafop Propargyl SCHEMBL28325546 0.79 L3MBTL1 (0.57) L3MBTL1LMNACYP2C9TSHRAPEX1
SCHEMBL8713988 0.79 L3MBTL1 (0.57) L3MBTL1LMNACYP2C9TSHRAPEX1
Clodinafop Propargyl SCHEMBL63886 0.79 L3MBTL1 (0.57) L3MBTL1LMNACYP2C9TSHRAPEX1
Clodinafop Propargyl SCHEMBL28237151 0.78 L3MBTL1 (0.56) L3MBTL1LMNACYP2C9TSHRAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0365484-B1 SULFAMOYL PHENYL UREAS CIBA-GEIGY AG (CH) 1993-01-07 EP claimed
EP-0365484-A1 Sulfamoyl phenyl ureas CIBA-GEIGY AG (CH) 1990-04-25 EP claimed
EP-0378508-B1 Antidotes to modify the resistance of cultivated plants to agrochemical agents CIBA GEIGY AG (CH) 1995-03-01 EP disclosed
US-5215570-A Plant safening agents CIBA-GEIGY CORPORATION (US) 1993-06-01 US disclosed
EP-0365484-B1 SULFAMOYL PHENYL UREAS CIBA-GEIGY AG (CH) 1993-01-07 EP disclosed
US-5175289-A Antidotes for protecting cultivated plants from the phytotoxic action of herbicides CIBA-GEIGY CORPORATION (US) 1992-12-29 US disclosed
US-5041157-A Protecting soybeans or cereals CIBA-GEIGY CORPORATION (US) 1991-08-20 US disclosed
EP-0378508-A2 Antidotes to modify the resistance of cultivated plants to agrochemical agents CIBA-GEIGY AG (CH) 1990-07-18 EP disclosed
EP-0365484-A1 Sulfamoyl phenyl ureas CIBA-GEIGY AG (CH) 1990-04-25 EP disclosed
EP-0335831-A1 Thiazole-5-carboxylic acid amides for protecting cultivated plants against the phytotoxic activity of highly active herbicides CIBA-GEIGY AG (CH) 1989-10-04 EP disclosed